Blood Group Genotyping

ReadyPlex™ – Rapid genotyping for blood grouping, Platelet (HPA), Neutrophils (HNA) and coagulation factors

(Currently in development and looking for commercialisation partners)

 

Real-time PCR blood group genotyping

The Biofortuna ReadyPlex™ product family is an exciting new range of real-time PCR-based products for genomic analysis of erythrocyte blood groups, Human Platelet Antigens (HPA), Human Neutrophil Antigens (HNA) and coagulation polymorphisms. The kits are ready to go – just add ReadyPlex mastermix combined with extracted DNA. After PCR, the ReadyPlex software enables easy genotyping.

 

HemoPlex™ RBC genotyping

A series of modular kits that can be used in combination to define a range of blood group genotypes, including the commonly requested RHD, RHCE, Kell, Kidd and Duffy polymorphisms.

Product NumberProduct NameSpecificationFormatTests per Kit
HP7HemoPlex Kell Genotyping KitDefines K, k, Kpa/b/c, Jsa, Jsb8 Reactions60
HP10HemoPlex MNS Genotyping KitMNS1(M), MNS2(N), MNS3(S), MNS4(s), U-, Uvar8 Reactions60
HP20HemoPlex ABO & RHD Screening KitABO screen, RHD+/-8 Reactions60
HP21HemoPlex ABO, RHDCE & Kell
Screening Kit
ABO genotyping, RHD/RHCE genotyping, Kell genotyping24 Reactions40
HP22HemoPlex Rhesus Genotyping KitRHD/RHCE genotyping plate32 Reactions30
HP24Hemoplex Multi-Blood Group Genotyping KitCartwright, Colton, Cromer, Diego, Duffy, Dombrock, Indian, Kidd, Knops, Landsteiner-W, Lutheran, MNS, OK, Scianna, Vel48 Reactions20
HP25HemoPlex Combi Blood Group
Genotyping Kit
ABO genotyping, RHD/RHCE genotyping, Kell genotyping, Cartwright, Colton, Cromer, Diego, Duffy, Dombrock, Indian, Kidd, Knops, Landsteiner-W, Lutheran, MNS, OK, Scianna, Vel96 Reactions10
HP26Hemoplex Prime Plus
Genotyping Kit
RHCE, RHD, Kell, Kidd, Duffy, MNS, Diego, Dombrock, Colton, Cartwright, Lutheran48 Reactions20
HP27Hemoplex Prime Genotyping KitRHCE, Kell, Kidd, Duffy, MNS, Dombrock32 Reactions30

 

ThromboPlex™ platelet genotyping

A set of modular kits that can be used for genotyping common HPA-1 to 5, 12 and 15 mutations, or a comprehensive test for all 29 HPA alleles.

Product NumberProduct NameSpecificationFormatTests per Kit
TP1ThromboPlex HPA Screening Kit HPA-1a/b, 2a/b, 3a/b, 4a/b, 5a/b, 12aw/bw, & 15a/b 8 Reactions60
TP3ThromboPlex HPA Genotyping Kit HPA-1a/b to 29bw 32 Reactions30

 

NeutroPlex™ neutrophil genotyping

Kits for HNA-1, 3, 4 and 5 screening.

Product NumberProduct NameSpecificationFormatTests per Kit
NP1NeutroPlex HNA Genotyping KitDefines A & B alleles of HNA1, 3, 4, 58 Reactions60

 

CoaguPlex™ coagulation factor genotyping

Kits for Factor V Leiden, Factor II G20210A and MTHFR (methylenetetrahydrofolate reductase) C677T.

Product NumberProduct NameSpecificationFormatTests per Kit
CG1CoaguPlex Genotyping Kit 1691G>A Factor V Leiden polymorphism,
prothrombin (factor II) 20210G>A, MTHFR C677T
8 Reactions60

 

Please enquire for other blood group antigens, kit combinations or polymorphisms

For Investigational Use Only. Products currently in development.

 

ReadyPlex workflow 

Biofortuna’s ReadyPlex kits analyze genomic DNA. Each PCR reaction has an internal positive control to verify successful amplification allowing confident allelic typing.